BIOL 205 Lecture Notes - Lecture 1: Angelina Jolie, Wilhelm Johannsen, Pax6
26 Nov 2017
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Angelina jolie had a double mastectomy and her ovaries removed, as she had her genome sequenced and was at an 85% chance of developing cancer. No correlation between age of mother when she conceives. Correlation between age of father when he fertilizes eggs. Tracing the origin of a new point mutation. Mother has two m copies, father has two f copies. Kid gets one m and one f and may receive different sets of mutations. Mouses did not speak, but did change their vocalizations (changed pitch, neuron connectivity) Wild type vs mutant eyeless" (pax-6 gene) Pax-6 mutations in mouse and humans cause absense of eyes. There is an evoluntionary conservation with this gene. All so different, but pax-6 is needed for proper eye developed properly. Ectopic eye production with eyeless genes produces eyes, but aren"t connected to nervous system and therefore can only work if they are plugged in".
