BIOL 103 Lecture 3: bio lec 1.5
9 Jun 2016
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Document Summary
Pancreas produces inactive enzymes; these have to be hydrolyzed made a little smaller this exposes their active site and they become active. Trypsinogen = inactive form of trypsin: enterokinase: is the protein that will hydrolyze it and make sure the active site is now seen. Enterokinase is produced by the intestinal glands that lines the small intestine. This means trypsinogen, the zymogen of trypsin, doesn"t even see enterokinase until after it is made in the pancreas, goes out through the pancreatic duct and actually found in the small intestine. Once it hits the small intestine, the enterokinase present will activate it. This ensures the pancreas itself never sees this active protease. Chymotrypsinogen requires trypsin to form chymotrypsin; occurs in small intestine. Digestion of fats: produces bile in which helps in fat digestion. And helps to maintain ph: like the pancreas, the liver also produces bicarbonate ions.
