BIOL 103 Lecture Notes - Olanzapine, Perphenazine, Cognitive Behavioral Therapy
Document Summary
Should be more focus on negative and cognitive symp since they are more strongly associated with social and occupational functioning. Neurocognitive deficits were assessed in 8 domains. The hypothesis that olazapine treatment would produce greater neurocognitve benefits after 52 weeks than risperidone or haloperidol tretannt was not confirmed since the 3 meds did not differ in their neurpognitve efficacy. Olanzapienn and risperidone treated patients improved on several domains including executive function, learning/memory, processing speed, attention/vigilicamce, verbal working memory, and motor functions. Risperidone treated patients improved on domains of visuosptail memory. Haloperidol treated ppl improved only on domains of learning/memory. Concluding that patients benefit most from olamnzapine and risperidone. Aripiprzaole and perphenazine concludeed that both meds can improve the symp in treatment resistant pl who did not response to olazine or risperdine. There"s a huge urge to figure out whether high mortality in s is due to disorder itself or due to meds.