BIOL 102 Lecture 7: Week 7 - Bio 102 Notes
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(i) evidence of diversity made dna more credible candidate for genetic material. (ii) ratio suggested a structural basis for dna. Griffith (cid:894)(cid:1005)(cid:1013)(cid:1006)(cid:1012)(cid:895): idea that (cid:862)traits(cid:863) are (cid:272)o(cid:374)ferred (cid:271)(cid:455) a (cid:272)he(cid:373)i(cid:272)al (cid:272)o(cid:373)po(cid:374)e(cid:374)t of a (cid:272)ell first implicated in studies. Avery (1944): separating dna, rna, and protein and assessing their ability to transform cells. Chargaff (1950): showed dna composition varies from species too next and amounts of bases. Franklin, watson, crick (1950s): establish the structure of dna as an antiparallel double helix. The difference between a nitrogenous base, a nucleoside and a nucleotide. Nitrogenous base: purines (adenine, guanine) and pyrimidines (thymine, uracil). Nucleoside: base plus a sugar, either ribose or deoxyribose. Nucleotides: compound consisting of a nucleoside linked to a phosphate group. #"s of phosphates: tmp-thymidine monophosphate, tdp, ttp. Sugar: atp, datp, ctp, dctp, gtp, dgtp, ttp, dttp. The left strand is 5 prime because the nucleotides are the "right way up"
