BCHM 102 Lecture Notes - Lecture 18: Collagen, Enteropeptidase, Acute Pancreatitis
2 Dec 2016
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Lecture objectives: understand the relationship between nitrogen metabolism and protein digestion, discuss protein digestion, understand the fates of amino acids. Contain c, h, o and n: unlike fats and carbohydrates, amino acids are not stored in the body i. e. there is no protein that is responsible for maintaining supply of amino acids for future use. From the diet: by de novo synthesis. Protein turnover: most proteins in the body are constantly being turned over in the body. Synthesized and degraded/removed: permits the removal of abnormal or unneeded proteins (cid:894)e. g. fasted state (cid:449)e do(cid:374)"t (cid:374)eed glycogen) Concentration of a protein is controlled one of 2 ways: Synthesis is regulated determining concentration while degradation plays a minor role. Synthesis is constant, and amounts of protein are controlled by regulated degradation. In healthy adults, total amount of protein is constant: rate of protein synthesis is just sufficient to replace protein that is degraded.
