ANAT 216 Lecture 12: lecture_12_lymphatic_and_immune_system_lecture_2

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Lymphatic/immune system: lecture 2 (organs) (reading material: chapter 23: pages 617-624) Separated from surrounding tissues by a fibrous connective tissue capsule. Lymphoid organs (lymph nodes, thymus, spleen): diffuse lymphatic tissue and lymphatic follicles or nodules enclosed by a connective tissue capsule. Located throughout the body (pg 608 good representation) Monitor/ filter composition of circulating lymph before it reaches the venous system. function. Largest lymph nodes found where peripheral lymphatics connect with the trunk. structure: shape and size. Small lymphoid organs ranging from 1 25 mm. Trabeculae fibrous extensions from the fibrous capsule of lymph nodes. Outer cortex: contains aggregated b cells with germinal centers. Deep cortex: dominated by t cells cortex: follicles (nodules) with germinal centers diffuse tissue continuation of the cortex contains b cells, plasma cells and macrophages medulla: Medullary cords: b cells, macrophages and plasmocytes organized into elongated masses. T are cells in pericordical region between cortex and medulla sinuses: Present through the entirety of the lymph node.

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