ANAT 100 Lecture Notes - Lecture 2: Bone Marrow, Perichondrium, Axial Skeleton

• School: Queen's University
• Department: Anatomy and Cell Biology
• Course: ANAT 100
• Professor: Leslie W Mac Kenzie

Document Summary

Includes: cartilage and bones, semisolid and solid extracellular matrix. Cartilage: firm, gel-like extracellular matrix: composed of protein fibers and ground substance. Chondrocytes: matured cartilage cell, occupies space called lacunae, which is within extracellular matrix: chondrocytes prevent blood vessel formation via chemicals within extracellular matrix, this is called. Cartilage is stronger and more resilient than any other connective tissue, more flexible than bones. Strength in cartilage is from collagen fibers, resilience from elastic fibers and amount of ground substance. Cartilage is covered by perichondrium, there are two layers: outer layer-fibrous region, dense irregular ct. Protection and mechanical support, secures perichondrium to cartilage and other structures. Have stem cells (chondroblasts), which is responsible for growth and maintenance of cartilage. Function: support soft tissue, model for future bone growth. Location: articular end of bones, most of larynx, nose, trachea, costal cartilage (cartilage on ribs) Location: intervertebral discs, menisci (in knees) and between anterior parts of pelvic bone.