PSYCH 3FA3 Lecture Notes - Lecture 3: Bicuculline, Synaptic Plasticity, Pyramidal Cell
Document Summary
Strengthening of horizontal cortical connections following skill learning. Long-term depression (ltd) an activity-dependent reduction in the efficacy of neuronal synapses lasting hours or longer following a long patterned stimulus in a low frequency. Long-term potentiation (ltp) persistent increase in synaptic strength (as measured by the amplitude of the epsp) that can be rapidly induced by brief neural activity. Rats trained to reach through a hole in a food box with a single forepaw in order to. Method retrieve small food pellets using a grasping motion. Training and subsequent practice lasted three or five successive days with one training session per day. Successful performance of this skill occurred in the first one or two sessions, and the remaining sessions consisted of repeated practice and refinement of the skill. By the final two days of training, all rats achieved a performance of about 1. 5 pellet retrievals per minute, with few errors in the reach, grasp or retrieval actions.
