PSYCH 3F03 Lecture Notes - Adipose Tissue, Saturated Fat, Insulin Resistance
4 Feb 2014
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Document Summary
Infection: pregnancy, other conditions of energetic stress. During energetic stress: fat mobilized and converted into saturated fat for the body to use. Inactive immune system consumes about 23% of overall metabolism! When activated by infection, increases even further: sepsis:>50, when you"re sick you eat more carbs and less fat and protein, energy comes from stored adipose tissue and glucose stored in liver. Immune response to infection requires: downregulation of energy expenditure in non essential tissues. Mobilization of fat and insulin resistance should co-occur together! The presence of saturated fatty acids and glucose in the blood stream may: signal infection, active immune pathway, trigger insulin resistance. Saturated fatty acids may be present due to diet from animal sources. In evolutionary environments: consumed with animal protein, wild animals are learner so less saturated fats. Intake also associated with carbs: mimics infection, starvation, or some other situation! It salvages brain immune system gets activated without any infection.
