PSYCH 2E03 Lecture Notes - Receptive Field, Metabotropic Glutamate Receptor 6, Retina

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13 Jun 2013
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Ampa/kainate receptor (ionotropic) depolarizes the bipolar cells receptors decides whether glutamate will excite or inhibit the bipolar cells. Bipolar and ganglion: no change in sign. Possible change between receptor and bipolar depending on the receptor: on or off. Baseline firing, spontaneous firing patterns, removal of bipolar cells there is still firing in ganglion cells but influences baseline of firing (rapidity) On-off receptive field circuitry and lateral inhibition lateral inhibition: inhibition transmitted laterally across a nerve circuit. Amacrine cells also contribute to the lateral inhibition. Projections of retina lateral geniculate nucleus-visual cortex and the visual pathway lateral geniculate nucleus-visual cortex-motor cortex and the accommodation reflex pathway. Hypothalamus-pineal gland circadian rhythm retina maintains its connections with different parts of the brain depending on the complexity of the stimulus. Optic radiation: fan out end up on visual cortex, primary visual cortex, area lateral geniculate nucleus: cluster of neurons number 17. Once the fibres have crossed they are called optic tract.

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