PSYCH 2AP3 Lecture Notes - Lecture 40: Dominie, Group Psychotherapy, Tardive Dyskinesia

• School: McMaster University
• Department: Psychology
• Course: PSYCH 2AP3
• Professor: Geoffrey Hall

Document Summary

Dopamine antagonists reduce symptoms: reduces positive, not negative, symptoms o beta- unspecific blocker of receptors, no reduction in symptoms; same effect as placebo. Kringlen: (1967): mz = 45%; dz = 15% Pollin (1969): mz = 43%; dz = 9% Gottesoman (1972): mz = 58%; dz = 12% Fischer (1973): mz = 56%; dz = 26% Gottesman (1982): mz = 46%; dz = 14% Mao inhibitors break down the neurotransmitters should make symptoms worse but they don"t: 3% of patients worsened o 70% patients unchanged o 26% of patients improved. Type i: excess dopaminergic activity: positive symptoms predominate, individuals in which predominantly show positive symptoms, usually acute, good prognosis, no structural brain damage, neuroleptics effective in treatment. Type ii: neuron loss: negative symptoms predominate o intellectual impairment, poor prognosis. Perhaps dominie receptors, not amount: two receptor types: d1, d2, effective drugs block d2 more than d1.