PSYCH 2AP3 Lecture Notes - Lecture 7: Heritability, Twin, Single-Nucleotide Polymorphism

• School: McMaster University
• Department: Psychology
• Course: PSYCH 2AP3
• Professor: Richard B Day

Document Summary

Mao: monoamine oxidase, enzyme that breaks down the molecules of neurotransmitters, leaving them unusable. Mao limits the activity of neurotransmitters in the synaptic cleft. Mao leaves broken down neurotransmitters available for reuptake into the pre- synaptic neuron through transporter molecules where they can be reused. Reuptake depends on how much neurotransmitter is present in the synaptic cleft and the amount of transport vesicles there are. There are receptors for the same neurotransmitters in both the pre and postsynaptic neurons. In presynaptic neuron, these are called auto receptors. Activity of any given synapse depends on the levels of neurotransmitters and how many receptors are on the post-synaptic neuron and pre-synaptic neurons. We do(cid:374)"t k(cid:374)o(cid:449) (cid:449)h(cid:455) the drugs that are pres(cid:272)ri(cid:271)ed to fi(cid:454) (cid:374)euro(cid:272)he(cid:373)istr(cid:455) ha(cid:448)e the affe(cid:272)ts that they do. Fewer dopamine receptors in caudate nucleus of the basal ganglion. Lower levels of neurotransmitters in general underaroused brains. Knockout mice with no dopamine transport protein show the symptoms of.