NURSING 2LA2 Lecture Notes - Lecture 6: Bronchopulmonary Dysplasia, Airway Obstruction, Parasympathetic Nervous System
18 Feb 2018
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Document Summary
Copd acute phase proteins: proteins whose plasma concentrations increase (positive acute-phase proteins) or decrease (negative acute-phase proteins) in response to inflammation. Aecopd: acute changes in symptoms (cough, dyspnea & sputum production) beyond what is considered normal variability in a patient, infection is the main cause. Airway smooth muscle: increased smooth muscle due to hypersensitivity of the bronchi with bronchoconstriction due to persistent inflammation. Alpha-1 antitrypsin: deficiency counteracts elastase release, causes destruction of elastin fibers in the lungs, eventual emphysema. Anticholinergic: inhibits acetylcholine (neurotransmitter for both sympathetic and parasympathetic) smooth muscle and most systems in the body have a stronger parasympathetic innervation. The predominant ns (parasympathetic) is inhibited most -> produces sympathetic effects asthma beta-2 agonist: binds to beta-2 receptors causing sympathetic effects of bronchodilation. Bronchopulmonary dysplasia: chronic lung disease that affects newborns (mostly premature) and infants. It results from damage to the lungs caused by mechanical ventilation (respirator) and long-term use of oxygen.
