NURSING 2LA2 Lecture Notes - Lecture 1: Hans Selye, Extracellular Fluid, Negative Feedback

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14th century stress: hardship, straits, adversity or affliction. 17th century stress: appeared in the context of physical sciences load defined as an external force stress ratio of internal force created by the load to the area over which the force acted strain deformation or distortion of the object. 19th & 20th (cid:272)e(cid:374)turies: stress a(cid:374)d strai(cid:374) were thought to (cid:271)e the (cid:272)ause of (cid:862)ill health(cid:863) a(cid:374)d (cid:862)(cid:373)e(cid:374)tal disease(cid:863) 20th century: stress drew considerable attention as both a health concern and research focus. Stress an orchestrated set of bodily responses to any form of noxious stimulus. The environment in which body cells live is not the external environment that surrounds the organism, but rather the local fluid environment that surrounds each cell: stable internal environment= central importance. Body fluids surrounding the cells and the various organ systems provide the means for exchange between the external and the internal environments.

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