MEDRADSC 2X03 Lecture Notes - Lecture 12: Congenital Disorder, Ionizing Radiation, Late Effect
24 Jun 2016
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Document Summary
Explain the difficulty of attributing to radiation dose the occurrence of a congenital anomaly. List the 3 classic effects of radiation on the embryo and fetus. Outline the effects of radiation during pre-implantation, organogenesis, fetal growth stage. Discuss the observed effects of medical radiation to the embryo and fetus. Discuss the relationship between childhood cancer and irradiation in utero. Discuss the limiting of occupational exposure for pregnant woman. Discuss the irradiation of a pregnant or potentially pregnant patients in terms of professional practices and education to the patient. An agent that can produce a congential anomaly or raise the incidence of an anomaly in the population. Thalidomide anti-nausea drug, adverse effects: sever stunting of arms/legs. Germ cells affected, mutation may be passed down through generations. Somatic cells affected in utero, expressed at birth, no germ cell effect. * irradiation of the embryo/fetus can lead to both!
