MEDRADSC 1B03 Lecture Notes - Lecture 3: Neutrophil, Phagocytosis, Immune System
29 Jun 2016
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Document Summary
Discuss the normal body defenses and the acute and chronic inflammatory changes that can occur in response to an injury. Differentiate between local and systemic effects resulting from the inflammatory response. Identify the various drug therapies available to treat inflammation. Mechanical barrier: skin, mucous membrane, tears, saliva. All are not open only when needed pre capillary sphincters restrict flow. Net hydrostatic (hydrostatic pressure at arteriole (cap) hydrostatic pressure from the interstitial fluid) pressure determines if the fluid, o2, electrolytes and nutrients will move out of the capillary. Fluid will move to the lower pressure on the venous side. Diffusion of the electrolytes, glucose, oxygen, and nutrients cross the membrane based on the concentration levels in the blood. Excess fluid in and any proteins are picked up from the interstitial area by the lymphatic system. 5 cardinal signs of inflammation: heat. Increased blood flow: swelling, pain, loss of function.
