LIFESCI 2N03 Lecture Notes - Lecture 61: Fatty Liver, Citric Acid Cycle, Acetyl-Coa

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Nutrient: any substance in food that the body can use to obtain energy, synthesize issues, or regulate physiological/physical funcions. Drug: a substance that can modify one or more of the body"s funcions. Alcohol: class of organic compounds containing hydroxyl (-oh) Drinking in moderaion may have beneits: reduced risk of heart atack, stroke, demenia, diabetes, and osteoporosis, lower mortality in adults >35 years (no beneits if younger or much older) Any beneits must be weighed against many harmful efects. Efects: lipid solvent: dissolve lipids out of membranes, penetrate cells, destroy cell structures, kills cells: toxic in relaively small amounts, efecive as skin disinfectants because can kill microbial cells. No digesion of alcohol, quick absorpion across stomach walls: slow absorpion if stomach full of food, paricularly carbs. Stomach: alcohol dehydrogenase: secreted by stomach to break down alcohol, less produced by women than men. Less alcohol dehydrogenase when fasing (protein deiciency) causes greater impairment; feel efects of alcohol faster.

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