LIFESCI 2N03 Lecture Notes - Lecture 16: Metabolic Disorder, Spinach, Pantothenic Acid
8 Feb 2016
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Document Summary
Casimir funk (1884-1967): isolated an amine (nitrogen containing functional group) in rice: discovered providing an amine improved the health of thiamin deprived chickens. Thiamin deprived = didn"t have any b1: referred to this amine as vital for life, therefore we now have vital amines or vitamins. Essential required in small units (micrograms) Organized as individual units (not chains like macronutrients) Do not contribute to energy needs (in tems of kcal: allows cells to utilize fat, carbs and protein, but does not provide direct energy. Classification: fat-soluble (a, d, e, k) water-soluble (b, c) B vitamins tend to be involved in metabolic pathways. Vitamin k synthesized by bacteria in small intestine. 8 b-vitamins: b1 (thiamin), b2 (riboflavin), b3 (niacin), biotin, pantothenic acid, b6, folate, b12. Absorbed directly through intestinal cells and into the cv system. If taken in large doses beyond what is needed, we will excrete it as urine after kidney filtration.
