KINESIOL 2Y03 Lecture Notes - Lecture 8: Chemical Synapse, Extracellular Fluid, Neurotransmission

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M em bran e po ten tial s an d. In a resting cell: extracellular fluid is positively charged and the cytosol is negatively charged: resting neurons has an inner voltage of -70 mv. Resting potential of the membrane (6 8: resting neurons have -70 mv, only at the neurons you can have a voltage difference; far regions are neutral, concentration highlights , extracellular fluid has higher concentration of, chloride (cl-) Sodium (na+: cytosol has higher concentration of, potassium (k+, proteins (anions, calcium (ca2+) Na outside already): pumps in 2 k to the cytosol. Two types of ion channels: leak (non-gated) ion channels mostly open, gated ion channels that open and close on demand and they can change membrane potential: Establishing the resting potential (15: na, k, and proteins are involved in the resting potential, na/k pump is always open and sets up a concentration gradient (high k inside, high na outside).

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