HTHSCI 2C06 Lecture Notes - Lecture 13: Glomerulonephritis, Hypocalcaemia, Acute Kidney Injury

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Chronic kidney disease (ckd) or chronic kidney failure is defined as a progressive loss in kidney function due to loss of nephrons, loss of glomerular filtration, tubular reabsorption capacity and loss of endocrine function. In canada there are approximately 1. 5 million people with chronic renal failure, and. Glomerular filtration rate is the best measure to determine kidney function as it a reflection of the number of functioning nephrons. Chronic kidney disease is defined as a glomerular filtration rate (gfr) of less than 60ml per minute for 3 or more months. Unfortunately due to the silent nature of these disease, diagnosis is often late in the disease, and thus treatments measures are intended to support the individual, and to preserve and prolong the last functioning nephrons. 64 year old woman with esrf as caused by pyelonephritis. Presented to er with a 2 day history of feeling unwell, accompanied by nausea and vomiting.

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