HTHSCI 1LL3 Lecture Notes - Lecture 2: Body Water, Adipose Tissue, Ion

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Fluid compartments: total body water = 40l. Intracellular 25l: extracellular 15l, extracellular fluid. Polarity of water: the shared electrons of the h o bonds are attracted to the oxygen molecule, this gives the hydrogen atoms a partial positive charge. It also gives the oxygen atom a partial negative charge: reminder, anything polar/ionic will dissolve in water, anything non-polar will repel water. Thermal regulation: water helps maintain body temperature in the narrow range compatible with life. It is resistant to temperature change and can dissipate heat from areas that generate it such as the brain: water also maintains or dissipates heat when blood vessels in the skin constrict or dilate, respectively. Biochemistry: sodium is the major extracellular cation ph, ph is a measure of acidity of alkalinity of solution, ph = -log[h+, ph in the blood must be maintained in a narrow range.

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