HTHSCI 1H06 Lecture Notes - Lecture 14: Glycogen, Facilitated Diffusion, Glucose Tolerance Test

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The symptom refers to the large amount of urine produced. The disease occurs when there are problems with the body"s regulation of serum glucose levels or antidiuretic hormone (adh) levels both of which are characterized by polyuria (large amount of urine produced) Urine is sweet because there is a lot of sugar in it. The is a lot of urine because the dissolved sugar in the urine draws water into the urine by osmosis. Lack of, or lack of response to adh. Adh is produced in the hypothalamus and released in the posterior pituitary. Common cause is a decrease or blockade of adh secretion. May be due to trauma to the stalk connection pituitary to the hypothalamus. Pituitary tumours or tumour surgery or infection can also lead to damage. Without adh water is not well reabsorbed back into the blood. Poor water reabsorption results in increased urine ow. Results from the kidney becoming insensitive to the adh.

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