HTHSCI 1H06 Lecture Notes - Lecture 10: Chronic Obstructive Pulmonary Disease, Antiporter, Renal Compensation

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Various ions play different roles that help maintain homeostasis. A major homeostatic challenge is keeping the h+ concentration (ph0 of body fluids at an appropriate level. The maintenance of acid-base balance is of critical important to normal cellular function. A diet larger of protein acidifies the blood. In a health person, several mechanisms help maintain the ph of systemic arterial blood between 7. 35 and 7. 45. Metabolic reactions often produce a huge excess of h+, the lack of any mechanism for the disposal of h+ would cause h+ in body fluids to rise quickly to a lethal level. Homeostasis of h+ concentration within a narrow range is essential to survival. Buffers prevent rapid, drastic changes in the ph of body fluids by converting strong acids and bases into weak acids and weak bases. Strong acids and strong bases lower and lower and raise the ph more readily.

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