HTHSCI 1H06 Lecture 6: 06 Muscle A&P

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Skeletal muscle: basal metabolic rate keep vital functions going such as breathing and keeping warm. Lines the hollow tubes of the body. Spindle shaped with a single nucleus, and no striations. Filaments are anchored to dense bodies on intermediate filament network. Dense bodies are a aggression of proteins that help to transmit force created by contractile filaments out of the ecm. Dense bodies are connected to intermediate filaments which are part of the cells cytoskeleton. Involuntary contractions occur slowly but smooth muscle can maintain prolonged tension (tone) Contraction is stimulated by the autonomic nervous system (neurotransmitters), pacemaker cells, hormones, stretching, etc. Striated muscles, and 1 or 2 branched nuclei, multinucleated. Function: to move blood through the circulatory system. Intercalated discs (icd) : specialized area where the cardiomyocytes connect. Contraction accounts for all voluntary body movement. Muscles have a rich blood capillaries: peripheral nerve axons originate from motor neuron cell bodies in the spinal cord.

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