HTHSCI 1H06 Lecture Notes - Lecture 5: Tranylcypromine, Acetylcholine, Monoamine Oxidase
19 Sep 2018
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Document Summary
Nerve conduction: movement of nerve impulses down a neuron. Neurotransmission: transmission of its own nerve impulse between the synapse. Direction of impulse is always away from the soma. On a cell membrane axon there will always be positive outside and negative inside. (rmp is about -70mv) 2. in axon becomes slightly +ve, so it triggers the next area to open voltage sensitive na+ channels. Shortly lived because voltage sensitive k+ channels open. Reverse conduction will not occur because of the refractory period. Assures transmission is a one way event. Stimulus strength is coded by frequency of charges, not amplitude since all ap"s are the same. Allows the cell to recover to the resting state. The ap jumps, it does not depolarize the whole membrane. This makes it go a lot faster. For big axons it is covered in myelin sheath. Waxy oily covering insulates the spot so the nodes of ranvier are the only spots that are depolarized.
