HTHSCI 1DT3 Lecture Notes - Lecture 15: Limb Perfusion, Basal-Cell Carcinoma, Xeroderma Pigmentosum
26 Dec 2020
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Uk incidence = 10 000/yr and 2000 deaths/yr. Sunlight: esp. intense exposure in early years. Grow slowly, metastasise late = better prognosis. Invade deeply and metastasis early = poor prog. Thickness of tumour to deepest point of dermal invasion. Excision + 2o margin excision depending on bres depth. Adjuvant chemo (may use isolated limb perfusion) Male sex (more tumours on trunk cf. females) Ulcerated lesion c hard, raised everted edges. Sun exposure: scalp, face, ears, lower leg. May arise in chronic ulcers: marjolin"s ulcer. Typically on the legs of older women. Above line from tragus angle of mouth. Mohs: complete circumferential margin assessment using frozen section histology. Ant. margin of scm at junction of upper and middle 3rd. May be difficult due to proximity of carotids. Small opening in lower 3rd of neck on ant. margin of scm. Between tonsillar fossa and ant. border of scm. Just anterior to upper 3rd of scm.
