HTHSCI 1DT3 Lecture Notes - Lecture 15: Innate Immune System, T Helper Cell, Adaptive Immune System
13 Aug 2020
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Document Summary
Mod. 3-6 overview of innate immunity 1. Definitions: differences in innate and adaptive immunity. Non-specific pamps (unchanged structure) that is present on large. Specific antigen (epitope), particular domain present on group of pathogens one pathogen. Memory present for quick recall response (t and b cells) Huge diversity, acquired during during evolution and encoded by genes. There are only 13 tlrs rearrangement of genes, human. Specialised cells like b cells and t macrophages, nk cells and neutrophils cells. Ifn will induce the recruitment of inflammatory cells nk cells are the first cells to arrive. Innate immunity covers infections allowing time for adaptive immune system to be activate (takes a week): t helper cells help to make igg from b cells which enable long lasting protection. Mod. 3-6 overview of innate immunity 2. Helper t (th) cells to help b cells in antigen specific antibody production. And defensins are bactericidal and antiviral.
