HISTORY 1M03 Lecture Notes - Lecture 2: Pyrimidine, Pyrophosphate, Guanine
25 Apr 2021
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Learning outcomes: learn and remember the basic structure of dna and rna, understand how to read the genetic code. 2 substituents: amine group at c-4, keto group at c-2, adenine. Pyrimidine ring fused to an imidazole ring: uracil (rna only) Heterocyclic (ring with at least 2 different elements: thymine (dna only) Heterocyclic (ring with at least 2 different elements: guanine. Heterocyclic (ring with at least 2 different elements) Pyrimidine ring fused to an imidazole ring. Rna is more readily hydrolyzed than dna due to the oh group on c-2 that makes. Can be hydrolyzed by adding base in a test tube. On a dna polymer, there is direction since one side has a hydroxyl and one side has a phosphate group. To add another nucleotide to the dna strand, we could do a condensation rxn between the oh and the phosphate group, but this isnt favorable.
