BIOLOGY 3UU3 Lecture Notes - Lecture 11: Big Bang, Blood Sugar, Nitrogen Balance
4 Apr 2016
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Document Summary
Metabolic cycle involves oxidaive phase (mitochondria), generaion of free radicals, creaing an oxidated environment that afects cysteine residues. Oxidaion/reducion regulates and is regulated by circadian clocks. Most abundant and criical system protecing cell is the glutathione, glutaredoxin and thioredoxin are connected. Nitric oxide (especially in males), nitrosylaion is another free radical important in signalling. Immune systems of plants and animals funcion similarly. Comes back to idea of fundamental conservaion of systems. Glycsosylaion addiion of sugar, more important in damage than in signalling, extremely important in diabetes. Free radicals regulate phosphatases and kinases located at speciic places in cell , act at speciic locaions (localized signalling) Ion channels, criical in inlow of nutrient, changes in ion concentraions, redox funcions, transports. Ions channels contribute to funcions of enurons and neurotransmiters. All neuroendocrine secreions (global regulaion by hormones, ph, excreion and detox, muscle contracions) Thing sbeing transported what kind of a signal.
