BIOLOGY 2B03 Lecture Notes - Lecture 1: Van Der Waals Force, Aromatic Amino Acids, Alpha Helix
Document Summary
Functions of proteins: cell communicaion, sensors and receptors for environmental changes, structural component of the cell, molecular motors transport, organelle idenity and funcion, enzymes, gene regulaion (acivators, silencer, modiiers) 4 diferent structures of proteins: globular proteins, donut-shaped with acive site in the middle, y-shape: recognizes anigens, viruses, and bacteria, small enzyme. Structure deines funcion and substrate + acivity domain. N-terminus made irst, addiional amino acids always added to c-terminus. Pepide bonds link amino acids together via condensaion reacion between amino group of one amino acid and carboxyl group of another. Polypepide has to be modiied in various ways for folding to occur (post-translaional) Amino structure: carboxyl group, amino group, r group, hydrogen, alpha carbon. Amino acids classiied into groups based on solubility in water or polarity of side chain. Physical property of molecule that can bond with water through hydrogen bond. Thermodynamically favoured to hide hydrophobic side chains from water. Hydrophilic molecule: charged polarized, form hydrogen bonds with water.
