BIOLOGY 2B03 Lecture Notes - Receptor Tyrosine Kinase, Mitogen-Activated Protein Kinase Kinase, Adenylyl Cyclase
Document Summary
Change in behaviour/change in response of the cell. Requires receptors: signal must be interpreted in some way. Signal might be received by different cells and elicit different response. Cell-cell signalling: transmitting information from one cell to another and inducing a change in behaviour )response) Direct cell-to-cell contact, junctions: quickly transmit information. Extracellular signalling molecules: cells that are far apart communicate cell-to-cell via plasmodesmata plants through secreting signal. Produced by signalling cells induce a specific response in target cells with receptors for ligand can be proteins. Responses include changes in gene transcription, cell division, growth, differentiation, changes in shape, movement, changes in metabolism. Signaling molecules and cell-surface receptors signalling cells: source of signal or ligand target cells: receptors that receive signal ligand & receptor: specificity and affinity are determined by molecular complementarity signal inducing cellular response = signal transduction pathway. All cells have the potential to respond however only those which have the target will respond.