BIOLOGY 2A03 Lecture Notes - Lecture 4: Aquaporin, Autocrine Signalling, Paracrine Signalling

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Transport down an electrochemical gradient and therefore does not require atp. Simple diffusion and carrier mediated diffusion: active transport. Transport against the gradient, does require atp or other source of energy such as energy stored in a sodium gradient. Primary active transport and secondary active transport. Think about glucose uptake from our digestive system, occurs in the small intestine. Involves co-transport across the membrane between the lumen and the epithelial cells and this is a secondary active transport system. Glucose is more abundant inside the cells its going into so its going against its gradient and sodium is pulling it in using the energy stored in the sodium (na/k atpase) When glucose moves along the baso- lateral membrane its moving with the gradient, its a passive process but requires a transporter- this is active transport. Osmosis: the passive diffusion of water across membrane, membranes are permeable to water due to its small size even though it is a polar molecule.

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