BIOLOGY 1M03 Lecture Notes - Lecture 1: Genetic Variation, Y Chromosome, Ujung Kulon National Park

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Genetic drift (stronger in small populations, decreases diversity) Non-random mating: biased gene flow between human. Inheritance of mtdna, adna, xdna, and ydna populations. Impact of selection on phenotypic variance and allelic diversity. Different mechanisms can maintain/increase or decrease phenotypic variance and diversity, but most decrease. The high frequency of this allele in some populations is best explained by heterozygote advantage related to malaria resistance. Is any change in allele frequencies in a population due to chance. It causes allele frequencies to drift up and down stochastically over time. Alleles will fluctuate over time but will always go towards fixation or extinction. Population size influences how quickly fixation/extinction occurs. Genetic drift is more pronounced in small populations than in large populations. Given enough time; however, genetic drift can be an important factor in even large populations. Fruit flies started with 0. 5 of a1, 0. 5 of a2. After random mating, large number of flies lost one or the other allele.

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