BIOLOGY 1M03 Lecture Notes - Lecture 6: Mns Antigen System, Genotype Frequency, Allele Frequency

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Chapter 25: the gene pool concept, hardy weinberg, had an approach to analyze the consequences of matings among all the individuals in a population. Imagined that all gametes produced in each generation go into a single group, A1 and a2: use p to denote a1; and q to denote a2. Since there are only 2 alleles, must add up to 1 (p + q =1: example. Step 1: p and q can have any value b/w 0-1. Suppose initial frequency of p is 0. 7, and q is 0. 3. Step 2: in gene pool, 70% of gametes carry a1 gene and 30% carry. Step 3: gamete mix at random to produce offspring. Each time gamete is involved in forming offspring 70% chance a1 and 30% a2. Step 4: because only 2 alleles present 3 possible genotypes (a1a1, Frequencies will be (p2, 2pq, and q2) respectively: genotype frequencies must add to 1 (p2+2pq+q2=1) In example would be 0. 49, 0. 42, 0. 09 respectively.

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