BIOLOGY 1M03 Lecture Notes - Lecture 5: Sickle-Cell Disease, Allele Frequency, Genetic Correlation
14 Jan 2017
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Studying natural selection: melanism in moths, antibiotic resistance, darwin"s finches. New study suggests that the appendix may not in fact be as vestigial" as the textbook suggests. The appendix could be a sanctuary for bacteria that helps restore the gut bacteria after you get sick. Clostridium difficile is a deadly pathogen that normally does not compete well with gut bacteria but can kill people after they have been on antibiotics. Individuals without an appendix were 4x more likely to have a reoccurrence of c. difficile. Hwe: estimated expected genotype frequencies from allele frequencies. Estimating allele frequencies from phenotype frequencies under the assumption of hwe. Evolution by natural selection is not goal directed. Adaptations do not occur because organisms want or need them. Animal behaviour is selfless and is for the good of the species. Individuals with self-sacrificing" alleles die and do not produce offspring. Individuals with selfish" alleles survive and produce offspring.
