BIOLOGY 1A03 Lecture Notes - Lecture 4: Wheeze, Hydrophile, Francis Collins

• School: McMaster University
• Department: Biology
• Course: BIOLOGY 1A03
• Professor: Kim Dej

Document Summary

The most common fatal genetic disease (1/3600 children born in canada), and is more prominent in people of european descent. Many effects on the body, but mostly affects digestion and lungs. With chronic persistence and bacterial infections, destruction of lungs leads to most prevalent cause of death. Airways are larger but there is mucous build up making it more difficult to breath, smaller place to move through. Because of blockage of liver and pancreatic ducts there is nutrition deficiency, also cannot absorb nutrients, many are malnourished. It can also build up in reproductive organs, in men it can lead to infertility. Lungs: thick, sticky, mucous buildup, bacterial infection, widened airway. Putting an endoscope into the airway and looking at what is there. Goblet cells secrete mucus which traps any dust particles and bacteria. Cilia motility and cilia generated flow push mucus up and out the trachea.