BIOLOGY 1A03 Lecture Notes - Lecture 11: Gamma Globulin, Transcription Factor Ii B, Reverse Transcriptase

• School: McMaster University
• Department: Biology
• Course: BIOLOGY 1A03
• Professor: Rosa Da Silva

Document Summary

Theme 3 module 3 & 4: review lecture. Within the core promoter area, transcription factors are there. Tatabox region both on template and non-template strand is recognized by transcription factor tfiid. 35 at the bre (b recognition element. Regulatory promoter areas are outside of these promoter regions- but generally close. In eukaryotes, the enhancer regions or regulatory promoter areas are pretty far from core promoter area. The way dna is wound up tightly into heterochromatin helps it to stay close enough so when transcription can occur, it"s still close enough. The trans factors = transcription factors, the ones binding & recognizing these regulatory areas. The actual binding is dependent on conformational shape. Zinc ngers still have alpha helices with loops & turns, but they need a zinc ion. Leucine zippers still have a helical structures connecting w/ dna but there are other helices to dimerize together via leucine-leucine bonds. These are 4 types of structures of transcription factors.