BIOLOGY 1A03 Lecture Notes - Lecture 1: Tetrameric Protein, Sith, Cyclic Adenosine Monophosphate

• School: McMaster University
• Department: Biology
• Course: BIOLOGY 1A03
• Professor: Ben J Evans

Document Summary

As cells utilize available nutrients, they detect environmental cues facilitating transition from glucose - lactose metabolism. (eg. Transcriptional response to the environment: as cells transition from glucose lactose metabolism, there is a concomitant increase in the amount of detectable b-galactosidase and lactose permease proteins. Once glucose is depleted, and the bacterial cells are starting to utilize lactose, that there is also an increase in the expression of b-galactosidase and lactose permease proteins. The expression of b-galactosidase and lactose permease occurs in response to lactose metabolism: when glucose-depleted mediums, these proteins produce are produced in response to environmental cues, and allows for the effective digesting of lactose. Lactose permease is a transport protein that sits in the bacterial cell membrane, and allows for transport of lactose into the bacterial cells. B-galactosidase protein is cytoplasmically situated bacterial enzyme, and cleaves imported lactose to its monomers, glucose and galactose: expression of these two proteins is linked based on their functional relatedness.