BIOCHEM 3H03 Lecture Notes - Lecture 4: Hypernatremia, Hyperlipidemia, Dehydration
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Number of paricles of solute dissolved into the solvent. Colligaive properies (boiling point, vapour pressure, osmoic pressure) Easiest to measure is looking at the freezing point depression (boiling plasma is hard end up cooking it) Can supercool a soluion without having it freeze. Comes back to natural freezing point of soluion. Using sensiive thermocouples, you can establish the freezing point. Consuming ethanol each paricle contributes to osmolality. What happens if there are osmoles in the soluion that are not normally there? (ethanol) Not the mass of the soluion number of paricles. 2 x sodium + glucose + urea , if you measured osmolality of a person with ethanol, it would be diferent than the calculated value are there other osmmoles that shouldn"t be there. Measure speciic gravity, relaing mass of soluion to an equal volume of water at 4 degrees (density test)