BIOCHEM 2EE3 Lecture 5: Module 1 – Lecture 2

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Building blocks have to synthesize various molecules to maintain us known as macromolecules. 3 essenial macromolecules; nucleic acids (nucleoides), proteins (amino acids), carbohydrates (sugars) 1" carbon can bind to 1 of 4 nitrogen bases (adenine, cytosine, guanine + thymine) building blocks are covalently bonded by 3"carbon + 5" phosphate: intertwined double helix is formed. Nucleic acids = carbon, hydrogen, oxygen, nitrogen + phosphorus. Made up of amino acids as building blocks 20 dif amino acids: each amino acid = 1 leter code. Although each amino acid is diferent they have the same backbone: backbone of each amino acid is composed of an amino group + a carboxyl group. The r group denotes the diferent amino acids that can be bound at this speciic site. The amino group reacts with the carboxyl of another amino acid to form a covalent pepide bond: coninues unil you obtain a large protein macromolecule, held together by covalent pepide bonds.

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