PSYT 301 Lecture Notes - Lecture 7: Cocaine Dependence, Stimulant, Vin Mariani
24 Feb 2016
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John pemberton created a similar product, but removed the alcohol when the city of. Atlanta banned alcohol, added soda water and kola nut syrup (containing caffeine), this was the beginning of coca-cola. At around the same time, with the invention of the syringe and needle, cocaine was used as a local anaesthetic until procaine was developing in 1918, which was devoid of the psychological and dependence-producing effects. Only in the late 1800s did the toxic effects of cocaine begin to worry policymakers, in. When sniffed, cocaine users might sniff around 50mg to 100mg of cocaine at a time, whereas smoking crack yields average doses in the range of 250mg to 1g. Pharmacokinetics: cocaine is absorbed from all sites of application, including the mucous membranes, the stomach and the lungs. When crack cocaine is smoked, absorption is rapid and complete, effects begin within seconds and peak at 5 minutes.
