PSYC 337 Lecture Notes - Lecture 15: Cholinesterase, Frontal Lobe, Mental Disorder
Document Summary
Two types: early onset (around age 50, highly genetically related) vs. sporadic alzheimer"s (common usually over 75) Demographics: by 2041 there will be a large increase in dementia in those over 75. System can"t tolerate this (lack of resources) Our population is aging, people are living longer and longer. Late onset vs. early onset (few cases before 50) Women are more likely to develop alzheimer"s. Not b/c women live longer, probably to do with. Insidious onset people think it"s not predictable (though some data says it. Memory issues personality changes, irritability, concentration, performance aphasia apraxia agnosia decreased knowledge of current events lack of awareness gait and motor disturbances loss of speech, 8-10 years from mild to severe bedridden etc. and death. Parallels general definition of dementia but with differences. 1) memory impairment a) cognitive disturbances b) disturbance in executive functioning. 4) cog deficits not due to medication etc. Concordance rates for males 44% f 58% vs. dizygotic 25% and 45%