PSYC 211 Lecture Notes - Lecture 4: Resting Potential, Tandem Pore Domain Potassium Channel, Neuroglia

• School: McGill University
• Department: Psychology
• Course: PSYC 211
• Professor: Jonathan Britt

Document Summary

I introduced you to the 5 proteins that are needed to setup the neuronal membrane potential, support action potentials and trigger the vesicular release or neurotransmitter. 1/ sodium potassium transport (requires atp; concentrates sodium and potassium outside and inside the cell, respectively). Just concentrates ions, potassium in and sodium out. 2/leak potassium channels (always open; sets up the resting membrane potential). 3/ sodium (to initiate and propagate the action potential). 4/ potassium (to restore the resting membrane potential). 5/ calcium (to release the neurotransmitter-containing vesicles). - into the synapse. They all have a distinct role in the action potential. If k+ ions have the freedom to leave whenever they want, enough of them will do so that the membrane potential of the cell will drop to -60mv. Although less than 0. 01% of the potassium ions that are inside the cell will leave it, this corresponds to tens of millions of potassium ions.