PHGY 212 Lecture Notes - Lecture 3: Immunoglobulin A, Placenta, Opsonin
1 Nov 2016
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Document Summary
Immunology lab: goals: exposure to wet-lab experiments using immunological techniques. Introduction to experimental design & execution of protocol: 3 lab experiments: interaction between antibodies & antigens, hemagglutination. Look, wherever all red means meat created and have agglutination: complement-mediated lysis, formation mac complex, see if get lysis of cells. Intensity of blue is measure of amount enzymatic activity. Immune system review: cells of immune system originate in bone marrow in thymus and transported to other secondary organs through circulatory system (spleen biggest, primary: thymus & bone marrow. Function: produce large repertoire of cells able to recognize and respond to foreign molecules + eliminate self-reactive cells. Secondary: spleen, lymph nodes, mucosal, basal and gut associated lymphoid tissue (malt/balt/galt), tonsils, adenoids, peyer"s patches. Function: provide place where cells can proliferate and mature, filter and trap antigens and allow cell-cell interaction. Serum: fluid component of uncoagulated blood: has immunoglobulin: organism hasn"t been exposed to antigen, no immunization.
