PHGY 209 Lecture Notes - Lecture 7: C3B, Complement Component 5A, Neutrophil
16 Sep 2016
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There is no antibody activity in albumin, all antibody activity was in. Globulin: molecules are hard to analyze because they are heterogeneous and spread and are from different families of molecules. Patient with cancer in the plasma multiple myeloma o end stage of. In the place where these cells are proliferating, it pokes holes in the bone. Basic structure of monomeric antibody molecule o four chains: 2 identical light chains (kappa or. Five classes determined by the heavy (h) chain ( delta, mu, gamma, alpha, epsilon) Two types determined by the light (l) chain kappa, lambda. Each chain has 2 identical h and 2 identical l chains: interchain and intrachain disulfide bonds are present between and within all chains. Fragments prepared by laboratory cleavage result in: fab = antigen binding fragment (at the. Hypervariable region ) o fc = crystallisable fragment determines the biological activity of the ig class, e. g. igm: complement binding. Iga: secretory properties (malt) crosses mucous membranes.
