PHGY 209 Lecture Notes - Lecture 7: Hematopoietic Stem Cell, White Blood Cells (Album), Blood Cell

• School: McGill University
• Department: Physiology
• Course: PHGY 209
• Professor: Alvin Shrier

Document Summary

Only blood cells with nucleus in mature form. All blood cells are derived from a common, multipotential (pluripotential) hematopoietic stem cell. All blood cells are derived from pluripotential stem cells which are in capable the becoming production of one group of blood cells. Under induction (stimulus the pluripotent become committed to one of three blood cell lines. Once the committed stem cells are stimulated they can undergo division and differentiation to give rise to progenitors that will ultimately become mature their appropriate in stem cells environment), cells of committed self-replication to of dedicated lineage. The cytokines influencing the proliferation (division) and differentiatio precursors are known as hematopoietic growth factors (hgfs). Under the injection of cytokines (hgfs), the pluripotent hematopoietic stem cell can become one of two stem cell types: Lymphoid stem cell: give rise to one type of white blood cell. Myeloid stem cell: give rise to red blood cells, multiple white blood cell types, and platelets.