PHGY 209 Lecture Notes - Lecture 19: Human Leukocyte Antigen, Lymph Node, Innate Lymphoid Cell

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Many aspects of immune systems: every body system is impacted by immune system: endocrine: diabetes, thyroiditis, cardio: coronary artery disease, neuro: ms. O i(cid:373)porta(cid:374)t that (cid:455)ou (cid:862)do(cid:374)"t k(cid:374)o(cid:449) (cid:449)hat (cid:455)ou"(cid:448)e got till it"s go(cid:374)e(cid:863) First child was fine but man transmitted aids to wife after daughter was born and when the second child was born he already had aids. This has led to many orphans: hiv does(cid:374)"t kill directly it kills cells that defend infection th helper cells (quarterback of immune system)and cd4+ Primary organs: develop in utero: stem cells from yolk sac and fetal liver, bone marrow, thymus gland. Secondary organs: populated from primary in utero: lymph nodes (cid:862)outside ski(cid:374)(cid:863) first prote(cid:272)tor, spleen largest lymph node in body, mucosa-associated lymphoid tissue (malt) same kind of cells as lymph nodes in gut and lungs. Immune system is as large as any other system but wide spread.

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