PHGY 209 Lecture Notes - Lecture 33: Locus Coeruleus, Stretch Reflex, Withdrawal Reflex
Document Summary
Measures neural activity in volts near scalp (cortical gray matter) When amplitude too high (spike) = seizure. Alpha rhythms when the person is alert can be indication of neural disease. Nrem: as sleep goes deeper ie raise in stage, amplitude raises, frequency decreases: note: stage 1 has a lower amplitude than the awake state, one alternates between the stages in 30-45min intervals (not progressive) Rem aka paradoxical sleep (~25% when young, decrease w/ age: paradoxical because it is a deep sleep stage yet has very low amplitude + fast frequencies, characterized by rapid eye movement. Physiological changes: increase in 1) eye movement, 2) skeletal muscle inhibition, 3) heart rate/respiration. Dopamine is interesting because pretty much all the addictive drugs enhance its neurotransmission: amphetamine = a drug producing higher focus/wakefulness. Experiment: mouse continues to push button w/ repeated stimulus to reward areas. Most psychoactive drugs are involved in the mesolimbic dopamine pathway.
