PHGY 209 Lecture Notes - Lecture 6: Complete Blood Count, Ultracentrifuge, Fibrinogen

• School: McGill University
• Department: Physiology
• Course: PHGY 209
• Professor: Ann Wechsler

Document Summary

Blood functions: transport (nutritive, respiratory, excretory, hormone, temp. regulation) ph balance, protection, carrier of diseases. Blood comprises both ecf (plasma) and icf (inside blood cells) Can be studied in vivo or in vitro. Hematocrit: % of total blood volume that"s occupied by rbcs (normal: ~45%) Total blood volume occupied by plasma = total blood volume - total blood volume x hematocrit. Cbc = complete blood count (recall chart in lab) ph of blood: 7. 30-7. 45 major function: transport (e. g. hormone) comprises both ecf (plasma) and icf (inside blood cells) ~7% body mass (5l) (70kg male) o o total blood volume that"s rbcs = ~2. 25l total blood volume that"s plasma = ~2. 75l. The rest = buffy layer (wbcs, platelets) o top to bottom: plasma, buffy layer, rbcs. Hematocrit (ht): the % of blood volume that"s rbcs. o. Ht = height of erythrocyte column / height of whole blood column x 100% Composition of plasma (similar to isf) o o.