PHGY 209 Lecture Notes - Lecture 16: Hemoglobin, Kidney Disease, Viscosity
30 Oct 2016
School
Department
Course
Professor
Document Summary
Increase blood viscosity: harder to pump blood via heart. Sluggish blood flow may cause blood clots. Decrease in o2 carrying capacity of blood. Decrease rbc count: normal 5-5. 5 and 4-5 for female. Hb content decreases: normal 16 male, 14 female. Causes (etiological classification: diminished production, abnormal site. Abnormality in bone marrow produce fewer cells. Due to exposed to radiation, chemicals, drugs. Classified as normocytic, normochromic: abnormal stimulus. Classification: normocytic, normochromic: inadequate raw materials. Increased requirements for rbc to carry o2: infancy, adolescence, pregnancy. Inadequate supplies to due to: failure to absorb fe, dietary deficiency, loss of fe in hemorrhage. Normal erythropoiesis: requires 25mg fe/d, destruction of 25mgfe/d. Women loss about 50ml blood / month. They lose the hemoglobin and iron in the blood. Women need 50mg/month or 2mg/d: ineffective maturation, caused by deficiencies off vitamin b12 and folic acid. Required for normal dna synthesis: classification: macrocytic, normochromic, folic acid. Usually dietary absence, overcooking vegetables: vitamin b12.
